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AKR1C3 Inhibitor I

Catalog#: 2403-25
Size: 25 mg
Price: 5325 (RMB)

Product Name: AKR1C3 Inhibitor I

Alternate Name/Synonyms: 3-(3,4-Dihydroisoquinolin2(1H)-ylsulfonyl)benzoic acid

Description: A highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3. In repeat assays it showed an IC₅₀ of 0.013 ± 0.003 μM for AKR1C3, compared with 20.3 ± 3.8 μM against AKR1C1 and >30 μM against AKR1C2 and AKR1C4. This inhibitor also showed displays potency in a cellular assay, blocking the ability of AKR1C3 to metabolize a proven substrate.

Peptide Sequence: No

Appearance: White solid

Formulation: N/A

CAS Number: N/A

Molecular Formula: C16H15NO4S

Molecular Weight: 317.36

Purity: ≥98% by HPLC


Storage Temp.: -20 ̊C

Shipping Conditions: gel pack

Handling: Protect from air and light


InChi: InChI=1S/C16H15NO4S/c18-16(19)13-6-3-7-15(10-13)22(20,21)17-9-8-12-4-1-2-5-14(12)11-17/h1-7,10H,8-9,11H2,(H,18,19)


PubChem CID: N/A

MDL Number: N/A

USAGE: For Research Use Only! Not For Use in Humans.

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