Product Name: AKR1C3 Inhibitor I
Alternate Name/Synonyms: 3-(3,4-Dihydroisoquinolin2(1H)-ylsulfonyl)benzoic acid
Description: A highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3. In repeat assays it showed an IC₅₀ of 0.013 ± 0.003 μM for AKR1C3, compared with 20.3 ± 3.8 μM against AKR1C1 and >30 μM against AKR1C2 and AKR1C4. This inhibitor also showed displays potency in a cellular assay, blocking the ability of AKR1C3 to metabolize a proven substrate.
Peptide Sequence: No
Appearance: White solid
CAS Number: N/A
Molecular Formula: C16H15NO4S
Molecular Weight: 317.36
Purity: ≥98% by HPLC
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from air and light
InChi Key: ZGVIUMKHTXKKOX-UHFFFAOYSA-N
PubChem CID: N/A
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans.