Product Name: Irisin Antibody
Antibody Target: Irisin
Alternative Name: Fibronectin Type III Domain-containing Protein 5 (cleaved); Fibronectin Type III Repeat-containing Protein 2 (cleaved); FNDC5 (cleaved)
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Recombinant Irisin
Gene ID: 252995
Appearance: Colorless liquid
Concentration: 1 mg/ml
Formulation: 1 mg/ml in PBS containing 10% glycerol and 0.02% sodium azide.
Purification: Epitope affinity purified
Species Reactivity: Human, Mouse, Rat, Monkey
Application: Western blot
Positive Control: N/A
Application & Usage: Western Blot - 1: 1000 dilution
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Handling: The antibody solution should be gently mixed before use
USAGE: For Research Use Only! Not For Use in Humans.